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SHP620-302
Completed

A Study of Maribavir Compared to Valganciclovir to Treat Cytomegalovirus Infections in People Who Have Received Stem Cell Transplants

Clinicaltrials.gov
#NCT02927067
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About this clinical trial

This study is about treatment options for cytomegalovirus infections in people who have received stem cell transplants. The main aim of the study is to check if the cytomegalovirus infection can no longer be detected after treatment with marivabir or valganciclovir. Participants will take 2 tablets of marivabir or valganciclovir and 2 tablets of placebo twice a day for 8 weeks. A placebo will look like marivabir or valganciclovir but will not have any medicine in it. After treatment, each participant will be followed up for up to 12 weeks. Participants will visit their study clinic up to 18 times during the study.

US
ES
FR
20+
Interventional Phase 3 clinical trial.

At a glance

What medical conditions were being studied?

Cytomegalovirus (CMV)

What was the clinical trial testing?

Placebo, Maribavir, Valganciclovir

How many participants were enrolled?

553

Were placebos part of the clinical trial?

Yes

When was the clinical trial conducted?

Apr 2017 - Jul 2022

How long was participation in the clinical trial?

Each participant will be in the study for up to 22 weeks. This includes screening for the study.

Key requirements

Sexes

All

Age

16+ years

Healthy volunteers?

No

Entry criteria

Boys, girls, men, and women can take part.
Must 16 years or older.
Must be a recipient of hematopoietic stem cell transplant.
Must have a documented asymptomatic CMV infection.
Additional entry criteria will be discussed with the study doctor.

Study results

Locations